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yvrE [2019-07-10 10:56:57]
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yvrE [2019-07-10 10:56:57]

glucoco-lactonase, general stress protein, similar to senescence marker protein-30
locus
BSU33200
pI
4.62
mw
33.05 kDa
protein length
292 aa Sequence Blast
gene length
879 bp Sequence Blast
function
survival of salt stress
product
glucoco-lactonase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]
  • Gene

    Coordinates
    3,405,664 3,406,542

    The protein

    Catalyzed reaction/ biological activity

  • glucoco-lactonase [pubmed|29379263]
  • Protein family

  • SMP-30/CGR1 family (according to Swiss-Prot)
  • Structure

  • [PDB|3G4E] (the human protein, 33% identity) [pubmed|20329768]
  • Expression and Regulation

    Operons

    genes
    [gene|0F65F634368E935585FC015BA64085F3A2244F9B|yvrE]
    description
    [Pubmed|16306698]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]
  • view in new tab

    genes
    [gene|7098319D8E88FDC2A629A3F4A21507FD7A649385|yvrHb]-[gene|96E4470EF4B558F4EC318FEBF58B779BA50DB7E2|yvrG]-[gene|0F65F634368E935585FC015BA64085F3A2244F9B|yvrE]
    description
    [Pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-B048 (yvrE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1047 NBRP B. subtilis, Japan]
  • BKE33200 ([gene|0F65F634368E935585FC015BA64085F3A2244F9B|yvrE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTGTTACACCTCTTTAG, downstream forward: _UP4_TAAAAAAAACGCATCCGAAA
  • BKK33200 ([gene|0F65F634368E935585FC015BA64085F3A2244F9B|yvrE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTGTTACACCTCTTTAG, downstream forward: _UP4_TAAAAAAAACGCATCCGAAA
  • References

  • 15805528,16306698,29379263,20329768